Xencor, Inc. (XNCR)
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Xencor, Inc., a clinical stage biopharmaceutical company, focuses on the discovery and development of engineered monoclonal antibody and cytokine therapeutics to treat patients with cancer and autoimmune diseases. The company provides Sotrovimab that targets the SARS-CoV-2 virus; Ultomiris for the treatment of patients with paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome; and Monjuvi for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma. It develops Plamotamab, a tumor-targeted antibody, which is in Phase I clinical trial to treat non-Hodgkin lymphoma; Vudalimab, a bispecific antibody, which is in Phase II clinical trial to treat metastatic castration-resistant prostate cancer and other solid tumor types; and Tidutamab that is in Phase II clinical trial to treat neuroendocrine tumors. The company is also developing XmAb306, which is in Phase I clinical trial to treat solid tumors; XmAb104 and XmAb841, which are in Phase I clinical trial to treat patients with selected solid tumors; XmAb564 that is in Phase I clinical trial to treat autoimmune diseases; AMG 509, which is in Phase I clinical trial to treat prostate cancer; XmAb819 for patients with renal cell carcinoma; and Novartis XmAb. It develops VIR-3434, which is in Phase II clinical trial for patients with hepatitis B virus infection; VIR-2482 that is in Phase 1/2 clinical trial to trat influenza A; VIR-7832, which is in Phase 1b/2a trial to treat mild-to-moderate COVID-19; and BMS-986414 + BMS-986413 is in Phase 2/3 NIH ACTIV-2 trial in treating COVID-19. The company develops AIMab7195 to reduce blood serum levels of IgE that mediates allergic responses and allergic disease; Obexelimab to treat autoimmune disease; and Xpro1595 to treat patients with Alzheimer's disease, mild cognitive impairment, and depression. It has a license agreement with Caris Life Sciences. Xencor, Inc. was incorporated in 1997 and is headquartered in Monrovia, California.
NEWS

Xencor Announces Extension of U.S. Patent Term on Certain Xtend™ Antibodies
businesswire.com
2025-12-09 07:00:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today announced the issuance of U.S. Patent 12,492,253, which covers Xencor's Xtend™ Fc domain for extending the half-life of antibodies targeting C5, with a term that extends into December 2028. The new patent term is approximately three years longer than the previous latest-to-expire U.S. patent covering.

Xencor to Participate at Upcoming Investor Conferences
businesswire.com
2025-11-10 16:01:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today announced that company management will participate at multiple upcoming investor conferences: TD Cowen Immunology and Inflammation Virtual Summit Date: Wednesday, November 12, 2025 Presentation Time: 3:00 p.m. ET / 12:00 p.m. PT Piper Sandler 37th Annual Healthcare Conference Date: Tuesday, December.

Y Intercept Hong Kong Ltd Purchases 46,140 Shares of Xencor, Inc. $XNCR
defenseworld.net
2025-11-06 04:00:58Y Intercept Hong Kong Ltd grew its position in shares of Xencor, Inc. (NASDAQ: XNCR) by 93.0% in the second quarter, according to its most recent filing with the SEC. The fund owned 95,745 shares of the biopharmaceutical company's stock after acquiring an additional 46,140 shares during the quarter. Y Intercept Hong Kong

Xencor (XNCR) Reports Q3 Loss, Misses Revenue Estimates
zacks.com
2025-11-05 18:36:05Xencor (XNCR) came out with a quarterly loss of $0.08 per share versus the Zacks Consensus Estimate of a loss of $0.72. This compares to a loss of $0.71 per share a year ago.

Xencor Reports Third Quarter 2025 Financial Results
businesswire.com
2025-11-05 16:01:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today reported financial results for the third quarter ended September 30, 2025 and provided recent business and clinical program updates. “Xencor's two novel, first-in-class, CD3 T-cell engaging bispecific antibodies, XmAb819 and XmAb541, have demonstrated compelling clinical data in advanced clear cell r.

Xencor (XNCR) Projected to Post Earnings on Wednesday
defenseworld.net
2025-11-04 04:23:04Xencor (NASDAQ: XNCR - Get Free Report) is expected to post its Q3 2025 results before the market opens on Wednesday, November 5th. Analysts expect Xencor to post earnings of ($0.72) per share and revenue of $29.7290 million for the quarter. Individuals can find conference call details on the company's upcoming Q3 2025 earningreport page for

Xencor, Inc. (XNCR) Discusses Initial Phase I Dose Escalation Results for XmAb819 in Advanced Clear Cell Renal Cell Carcinoma Transcript
seekingalpha.com
2025-10-24 17:37:40Xencor, Inc. (NASDAQ:XNCR ) Discusses Initial Phase I Dose Escalation Results for XmAb819 in Advanced Clear Cell Renal Cell Carcinoma October 24, 2025 1:30 PM EDT Company Participants Charles Liles - Associate Director and Head of Corporate Communications & Investor Relations Bassil Dahiyat - Co-Founder, CEO, President & Director John Desjarlais - Executive VP of Research & Chief Scientific Officer Dane Leone - Executive VP & Chief Strategy Officer Conference Call Participants Sumanta Kumar Pal Steven Seedhouse - Cantor Fitzgerald & Co., Research Division Jonathan Chang - Leerink Partners LLC, Research Division Sean McCutcheon - Raymond James & Associates, Inc., Research Division Matthew Phipps - William Blair & Company L.L.C., Research Division Tara Bancroft - TD Cowen, Research Division Eva Fortea-Verdejo - Wells Fargo Securities, LLC, Research Division Alec Stranahan - BofA Securities, Research Division Lut Ming Cheng - JPMorgan Chase & Co, Research Division Presentation Operator Good day, everyone.

Xencor Presents Initial Data for XmAb819, a First-in-class ENPP3 x CD3 Bispecific T-Cell Engager, in Development for Clear Cell Renal Cell Carcinoma
businesswire.com
2025-10-24 12:30:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today announced initial results from the ongoing Phase 1 dose-escalation study of XmAb819, a ENPP3 x CD3 T-cell engaging bispecific antibody, in patients with advanced clear cell renal cell carcinoma (ccRCC). The results were presented in a poster at the AACR-NCI-EORTC Conference on Molecular Targets and C.

Xencor to Host Webcast and Conference Call to Discuss Initial Results from the Ongoing Phase 1 Dose-Escalation Study of XmAb819 in Advanced Clear Cell Renal Cell Carcinoma
businesswire.com
2025-10-21 08:01:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, will host a conference call and webcast on Friday, October 24 at 1:30 p.m. ET (10:30 a.m. PT) to discuss initial results from the ongoing Phase 1 dose-escalation study of XmAb819, an ENPP3 x CD3 T-cell engaging bispecific antibody, in development for patients with advanced clear cell renal cell carcinoma.

Xencor Announces Presentation of Initial Phase 1 Dose-Escalation Results of XmAb819 in Clear Cell Renal Cell Carcinoma at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
businesswire.com
2025-10-14 12:45:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today announced the upcoming presentation of initial results from the ongoing Phase 1 dose-escalation study of XmAb819, a bispecific ENPP3 x CD3 T-cell engaging bispecific antibody, in patients with clear cell renal cell carcinoma (ccRCC) in a poster at the AACR-NCI-EORTC Conference on Molecular Targets an.

Peanut Allergy Clinical Trial Pipeline: Insights into a Growing Landscape with 12+ Companies Advancing Novel Treatments| DelveInsight
globenewswire.com
2025-09-29 17:00:00Peanut allergy is a growing health concern, especially in children, with rising incidence and increased public awareness of its severity and risks. This

Xencor: Bispecific Antibody Program Takes Shape With Q4 Data Release
seekingalpha.com
2025-09-19 17:35:33Xencor remains a "Strong Buy" rating due to progress in its bispecific and monospecific antibody pipeline targeting inflammatory disorders and cancer. XNCR's XmAb942 anti-TL1A antibody is advancing toward a phase 2b trial in ulcerative colitis in 2nd half of 2025, with positive interim safety and biomarker data already reported. XmAb819, a 2+1 bispecific antibody for relapsed/refractory ccRCC, has shown early anti-tumor activity; initial phase 1 data is expected in Q4 2025.

Strength Seen in Xencor (XNCR): Can Its 7.3% Jump Turn into More Strength?
zacks.com
2025-09-18 11:06:05Xencor (XNCR) saw its shares surge in the last session with trading volume being higher than average. The latest trend in earnings estimate revisions may not translate into further price increase in the near term.

Xencor (XNCR) Reports Q2 Loss, Tops Revenue Estimates
zacks.com
2025-08-06 18:36:07Xencor (XNCR) came out with a quarterly loss of $0.41 per share versus the Zacks Consensus Estimate of a loss of $0.78. This compares to a loss of $1.07 per share a year ago.

Xencor Reports Second Quarter 2025 Financial Results
businesswire.com
2025-08-06 16:01:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today reported financial results for the second quarter ended June 30, 2025 and provided recent business and clinical program updates. "Xencor is focused on execution of our clinical studies, evaluating four wholly owned XmAb® drug candidates in cancer and advanced autoimmune-driven diseases,” said Bassil.
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Xencor Announces Extension of U.S. Patent Term on Certain Xtend™ Antibodies
businesswire.com
2025-12-09 07:00:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today announced the issuance of U.S. Patent 12,492,253, which covers Xencor's Xtend™ Fc domain for extending the half-life of antibodies targeting C5, with a term that extends into December 2028. The new patent term is approximately three years longer than the previous latest-to-expire U.S. patent covering.

Xencor to Participate at Upcoming Investor Conferences
businesswire.com
2025-11-10 16:01:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today announced that company management will participate at multiple upcoming investor conferences: TD Cowen Immunology and Inflammation Virtual Summit Date: Wednesday, November 12, 2025 Presentation Time: 3:00 p.m. ET / 12:00 p.m. PT Piper Sandler 37th Annual Healthcare Conference Date: Tuesday, December.

Y Intercept Hong Kong Ltd Purchases 46,140 Shares of Xencor, Inc. $XNCR
defenseworld.net
2025-11-06 04:00:58Y Intercept Hong Kong Ltd grew its position in shares of Xencor, Inc. (NASDAQ: XNCR) by 93.0% in the second quarter, according to its most recent filing with the SEC. The fund owned 95,745 shares of the biopharmaceutical company's stock after acquiring an additional 46,140 shares during the quarter. Y Intercept Hong Kong

Xencor (XNCR) Reports Q3 Loss, Misses Revenue Estimates
zacks.com
2025-11-05 18:36:05Xencor (XNCR) came out with a quarterly loss of $0.08 per share versus the Zacks Consensus Estimate of a loss of $0.72. This compares to a loss of $0.71 per share a year ago.

Xencor Reports Third Quarter 2025 Financial Results
businesswire.com
2025-11-05 16:01:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today reported financial results for the third quarter ended September 30, 2025 and provided recent business and clinical program updates. “Xencor's two novel, first-in-class, CD3 T-cell engaging bispecific antibodies, XmAb819 and XmAb541, have demonstrated compelling clinical data in advanced clear cell r.

Xencor (XNCR) Projected to Post Earnings on Wednesday
defenseworld.net
2025-11-04 04:23:04Xencor (NASDAQ: XNCR - Get Free Report) is expected to post its Q3 2025 results before the market opens on Wednesday, November 5th. Analysts expect Xencor to post earnings of ($0.72) per share and revenue of $29.7290 million for the quarter. Individuals can find conference call details on the company's upcoming Q3 2025 earningreport page for

Xencor, Inc. (XNCR) Discusses Initial Phase I Dose Escalation Results for XmAb819 in Advanced Clear Cell Renal Cell Carcinoma Transcript
seekingalpha.com
2025-10-24 17:37:40Xencor, Inc. (NASDAQ:XNCR ) Discusses Initial Phase I Dose Escalation Results for XmAb819 in Advanced Clear Cell Renal Cell Carcinoma October 24, 2025 1:30 PM EDT Company Participants Charles Liles - Associate Director and Head of Corporate Communications & Investor Relations Bassil Dahiyat - Co-Founder, CEO, President & Director John Desjarlais - Executive VP of Research & Chief Scientific Officer Dane Leone - Executive VP & Chief Strategy Officer Conference Call Participants Sumanta Kumar Pal Steven Seedhouse - Cantor Fitzgerald & Co., Research Division Jonathan Chang - Leerink Partners LLC, Research Division Sean McCutcheon - Raymond James & Associates, Inc., Research Division Matthew Phipps - William Blair & Company L.L.C., Research Division Tara Bancroft - TD Cowen, Research Division Eva Fortea-Verdejo - Wells Fargo Securities, LLC, Research Division Alec Stranahan - BofA Securities, Research Division Lut Ming Cheng - JPMorgan Chase & Co, Research Division Presentation Operator Good day, everyone.

Xencor Presents Initial Data for XmAb819, a First-in-class ENPP3 x CD3 Bispecific T-Cell Engager, in Development for Clear Cell Renal Cell Carcinoma
businesswire.com
2025-10-24 12:30:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today announced initial results from the ongoing Phase 1 dose-escalation study of XmAb819, a ENPP3 x CD3 T-cell engaging bispecific antibody, in patients with advanced clear cell renal cell carcinoma (ccRCC). The results were presented in a poster at the AACR-NCI-EORTC Conference on Molecular Targets and C.

Xencor to Host Webcast and Conference Call to Discuss Initial Results from the Ongoing Phase 1 Dose-Escalation Study of XmAb819 in Advanced Clear Cell Renal Cell Carcinoma
businesswire.com
2025-10-21 08:01:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, will host a conference call and webcast on Friday, October 24 at 1:30 p.m. ET (10:30 a.m. PT) to discuss initial results from the ongoing Phase 1 dose-escalation study of XmAb819, an ENPP3 x CD3 T-cell engaging bispecific antibody, in development for patients with advanced clear cell renal cell carcinoma.

Xencor Announces Presentation of Initial Phase 1 Dose-Escalation Results of XmAb819 in Clear Cell Renal Cell Carcinoma at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
businesswire.com
2025-10-14 12:45:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today announced the upcoming presentation of initial results from the ongoing Phase 1 dose-escalation study of XmAb819, a bispecific ENPP3 x CD3 T-cell engaging bispecific antibody, in patients with clear cell renal cell carcinoma (ccRCC) in a poster at the AACR-NCI-EORTC Conference on Molecular Targets an.

Peanut Allergy Clinical Trial Pipeline: Insights into a Growing Landscape with 12+ Companies Advancing Novel Treatments| DelveInsight
globenewswire.com
2025-09-29 17:00:00Peanut allergy is a growing health concern, especially in children, with rising incidence and increased public awareness of its severity and risks. This

Xencor: Bispecific Antibody Program Takes Shape With Q4 Data Release
seekingalpha.com
2025-09-19 17:35:33Xencor remains a "Strong Buy" rating due to progress in its bispecific and monospecific antibody pipeline targeting inflammatory disorders and cancer. XNCR's XmAb942 anti-TL1A antibody is advancing toward a phase 2b trial in ulcerative colitis in 2nd half of 2025, with positive interim safety and biomarker data already reported. XmAb819, a 2+1 bispecific antibody for relapsed/refractory ccRCC, has shown early anti-tumor activity; initial phase 1 data is expected in Q4 2025.

Strength Seen in Xencor (XNCR): Can Its 7.3% Jump Turn into More Strength?
zacks.com
2025-09-18 11:06:05Xencor (XNCR) saw its shares surge in the last session with trading volume being higher than average. The latest trend in earnings estimate revisions may not translate into further price increase in the near term.

Xencor (XNCR) Reports Q2 Loss, Tops Revenue Estimates
zacks.com
2025-08-06 18:36:07Xencor (XNCR) came out with a quarterly loss of $0.41 per share versus the Zacks Consensus Estimate of a loss of $0.78. This compares to a loss of $1.07 per share a year ago.

Xencor Reports Second Quarter 2025 Financial Results
businesswire.com
2025-08-06 16:01:00PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today reported financial results for the second quarter ended June 30, 2025 and provided recent business and clinical program updates. "Xencor is focused on execution of our clinical studies, evaluating four wholly owned XmAb® drug candidates in cancer and advanced autoimmune-driven diseases,” said Bassil.










