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    Karyopharm Therapeutics Inc. (KPTI)

    Price:

    5.90 USD

    ( + 0.13 USD)

    Your position:

    0 USD

    ACTION PANEL
    CREATE A NOTE
    ABOUT
    Symbol
    KPTI
    Name
    Karyopharm Therapeutics Inc.
    Industry
    Biotechnology
    Sector
    Healthcare
    Price
    5.900
    Market Cap
    51.161M
    Enterprise value
    214.427M
    Currency
    USD
    Ceo
    Richard A. Paulson
    Full Time Employees
    279
    Ipo Date
    2013-11-06
    City
    Newton
    Address
    85 Wells Avenue

    Check the

    KEY TAKEAWAYS

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    SIMILAR COMPANIES STI SCORE

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    Regeneron Pharmaceuticals, Inc.

    VALUE SCORE:

    6

    Symbol
    REGN
    Market Cap
    60.756B
    Industry
    Biotechnology
    Sector
    Healthcare

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    Harmony Biosciences Holdings, Inc.

    VALUE SCORE:

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    Symbol
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    Market Cap
    1.531B
    Industry
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    Sector
    Healthcare

    The best

    Agios Pharmaceuticals, Inc.

    VALUE SCORE:

    12

    Symbol
    AGIO
    Market Cap
    2.453B
    Industry
    Biotechnology
    Sector
    Healthcare
    FUNDAMENTALS
    P/E
    -0.412
    P/S
    0.373
    P/B
    -0.213
    Debt/Equity
    -0.397
    EV/FCF
    -1.042
    Price to operating cash flow
    -1.000
    Price to free cash flow
    -1.000
    EV/sales
    0.781
    Earnings yield
    -2.430
    Debt/assets
    0.904
    FUNDAMENTALS
    Net debt/ebidta
    -0.729
    Interest coverage
    -2.571
    Research And Developement To Revenue
    0.997
    Intangile to total assets
    0
    Capex to operating cash flow
    -0.001
    Capex to revenue
    0.000
    Capex to depreciation
    -0.028
    Return on tangible assets
    -1.178
    Debt to market cap
    1.853
    Piotroski Score
    4.000
    FUNDAMENTALS
    PEG
    0.004
    P/CF
    -0.421
    P/FCF
    -0.424
    RoA %
    -117.818
    RoIC %
    -1.634k
    Gross Profit Margin %
    96.370
    Quick Ratio
    0.936
    Current Ratio
    0.986
    Net Profit Margin %
    -90.017
    Net-Net
    -30.732
    FUNDAMENTALS PER SHARE
    FCF per share
    -11.936
    Revenue per share
    15.924
    Net income per share
    -14.335
    Operating cash flow per share
    -11.942
    Free cash flow per share
    -11.936
    Cash per share
    5.997
    Book value per share
    -27.718
    Tangible book value per share
    -27.718
    Shareholders equity per share
    -27.718
    Interest debt per share
    16.196
    TECHNICAL
    52 weeks high
    16.950
    52 weeks low
    3.510
    Current trading session High
    6.110
    Current trading session Low
    4.510
    DIVIDEND
    Dividend yield
    0.00%
    Payout ratio
    0.00%
    Years of div. Increase
    0
    Years of div.
    0
    Q-shift
    Dividend per share
    0
    SIMILAR COMPANIES
    logo

    Country
    US
    Sector
    Healthcare
    Industry
    Biotechnology
    Dividend yield
    0%
    Payout Ratio
    0%
    P/E
    3.762
    logo

    Country
    US
    Sector
    Healthcare
    Industry
    Biotechnology
    Dividend yield
    0%
    Payout Ratio
    0%
    P/E
    1.137
    logo

    Country
    US
    Sector
    Healthcare
    Industry
    Biotechnology
    Dividend yield
    0%
    Payout Ratio
    0%
    P/E
    -224.164
    logo

    Country
    US
    Sector
    Healthcare
    Industry
    Biotechnology
    Dividend yield
    0%
    Payout Ratio
    0%
    P/E
    -3.096
    logo

    Country
    US
    Sector
    Healthcare
    Industry
    Biotechnology
    Dividend yield
    0%
    Payout Ratio
    0%
    P/E
    -2.983
    logo

    Country
    US
    Sector
    Healthcare
    Industry
    Biotechnology
    Dividend yield
    0%
    Payout Ratio
    0%
    P/E
    5.314
    logo

    Country
    US
    Sector
    Healthcare
    Industry
    Biotechnology
    Dividend yield
    0%
    Payout Ratio
    0%
    P/E
    88.591
    DESCRIPTION

    Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases. The company discovers, develops, and commercializes novel and Selective Inhibitor of Nuclear Export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1. Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma, and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. The company has license agreement with Menarini Group to develop and commercialize NEXPOVIO for human oncology indications in Europe, including the United Kingdom; Latin America; and other countries. Its oral SINE compounds also designed to force nuclear accumulation in the levels of multiple tumor suppressor and growth regulatory proteins. The company was incorporated in 2008 and is headquartered in Newton, Massachusetts.

    NEWS
    https://images.financialmodelingprep.com/news/karyopharm-strengthens-balance-sheet-with-100-million-financing-to-20251008.jpeg
    Karyopharm Strengthens Balance Sheet With $100 Million Financing To Extend Cash Runway Into 2026

    benzinga.com

    2025-10-08 13:31:59

    Karyopharm Therapeutics Inc. (NASDAQ:KPTI) on Wednesday announced comprehensive financing and capital structure transactions expected to provide the company with  $100 million of financial flexibility and additional capital, extending the cash runway into the second quarter of 2026.

    https://images.financialmodelingprep.com/news/karyopharm-announces-strategic-financing-transactions-to-support-growth-extends-20251008.jpg
    Karyopharm Announces Strategic Financing Transactions to Support Growth; Extends Cash Runway Into Second Quarter of 2026, Beyond Expected Top-Line Readout of Phase 3 SENTRY Trial in Myelofibrosis

    prnewswire.com

    2025-10-08 07:00:00

    – Transactions Provide Karyopharm with $100 Million of Financial Flexibility and Additional Capital – – Preliminary Total Revenue and U.S. XPOVIO® (selinexor) Net Product Revenue for the Third Quarter of 2025 Expected to be in the Range of $42 to $44 Million and Approximately $32 Million, Respectively – – Top-Line Data from the Phase 3 SENTRY Trial in Myelofibrosis on Track for March 2026 – NEWTON, Mass. , Oct. 8, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that it has entered into  comprehensive financing and capital structure transactions expected to provide the Company with  $100 million of financial flexibility and additional capital, extending the Company's cash runway into the second quarter of 2026 based on the Company's current operating plans.

    https://images.financialmodelingprep.com/news/karyopharm-therapeutics-reports-inducement-grants-under-nasdaq-listing-rule-20251001.jpg
    Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

    prnewswire.com

    2025-10-01 16:05:00

    NEWTON, Mass. , Oct. 1, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted an aggregate of 333 restricted stock units (RSUs) to one newly-hired employee.

    https://images.financialmodelingprep.com/news/karyopharm-therapeutics-kpti-moves-279-higher-will-this-strength-20250924.jpg
    Karyopharm Therapeutics (KPTI) Moves 27.9% Higher: Will This Strength Last?

    zacks.com

    2025-09-24 04:51:07

    Karyopharm Therapeutics (KPTI) witnessed a jump in share price last session on above-average trading volume. The latest trend in earnings estimate revisions for the stock doesn't suggest further strength down the road.

    https://images.financialmodelingprep.com/news/karyopharm-announces-completion-of-enrollment-in-the-phase-3-20250910.jpg
    Karyopharm Announces Completion of Enrollment in the Phase 3 SENTRY Trial in Myelofibrosis

    prnewswire.com

    2025-09-10 07:00:00

    – Top-Line Results Anticipated in March 2026 – NEWTON, Mass. , Sept. 10, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that it has completed enrollment in the Phase 3 SENTRY trial, which is evaluating selinexor in combination with ruxolitinib in JAKi-naïve myelofibrosis patients.

    https://images.financialmodelingprep.com/news/karyopharm-therapeutics-reports-inducement-grants-under-nasdaq-listing-rule-5635c4-20250902.jpg
    Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

    prnewswire.com

    2025-09-02 16:05:00

    NEWTON, Mass. , Sept. 2, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted an aggregate of 466 restricted stock units (RSUs) to two newly-hired employees.

    https://images.financialmodelingprep.com/news/karyopharm-therapeutics-kpti-reports-q2-loss-lags-revenue-estimates-20250811.jpg
    Karyopharm Therapeutics (KPTI) Reports Q2 Loss, Lags Revenue Estimates

    zacks.com

    2025-08-11 20:01:37

    Karyopharm Therapeutics (KPTI) came out with a quarterly loss of $4.32 per share versus the Zacks Consensus Estimate of a loss of $3.8. This compares to a loss of $3 per share a year ago.

    https://images.financialmodelingprep.com/news/karyopharm-therapeutics-inc-kpti-q2-2025-earnings-call-transcript-20250811.jpg
    Karyopharm Therapeutics Inc. (KPTI) Q2 2025 Earnings Call Transcript

    seekingalpha.com

    2025-08-11 11:02:45

    Karyopharm Therapeutics Inc. (NASDAQ:KPTI ) Q2 2025 Earnings Call August 11, 2025 8:00 AM ET Company Participants Brendan Twohig Strong - Corporate Participant SVP of Investor Relations & Corporate Communications - Corporate Participant Lori A. Macomber - EVP, CFO & Treasurer Reshma Rangwala - Executive VP, Chief Medical Officer & Head of Research Richard A.

    https://images.financialmodelingprep.com/news/karyopharm-reports-second-quarter-2025-financial-results-and-highlights-20250811.jpg
    Karyopharm Reports Second Quarter 2025 Financial Results and Highlights Recent Company Progress

    prnewswire.com

    2025-08-11 07:30:00

    – New Patient Screening for Phase 3 SENTRY Trial in Myelofibrosis Expected to Close This Week; Top-Line Results Anticipated in March 2026 – – Total Revenue was $37.9 Million; U.S. XPOVIO® (selinexor) Net Product Revenue was $29.7 Million, up 6% compared to Second Quarter of 2024 – – Reaffirms Full-Year 2025 Total Revenue Guidance of $140 Million to $155 Million; Updates U.S. XPOVIO Net Product Revenue Guidance to $110 Million to $120 Million – – The Company is Exploring Financing Transactions and Strategic Alternatives to Extend its Cash Runway and Maximize Value – – Conference Call Scheduled for Today at 8:00 a.m. ET – NEWTON, Mass.

    https://images.financialmodelingprep.com/news/karyopharm-to-report-second-quarter-2025-financial-results-on-20250805.jpg
    Karyopharm to Report Second Quarter 2025 Financial Results on August 11, 2025

    prnewswire.com

    2025-08-05 07:00:00

    -- Conference Call Scheduled for Monday, August 11, 2025, at 8:00 a.m. ET -- NEWTON, Mass.

    https://images.financialmodelingprep.com/news/karyopharm-therapeutics-reports-inducement-grants-under-nasdaq-listing-rule-20250801.jpg
    Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

    prnewswire.com

    2025-08-01 16:05:00

    NEWTON, Mass. , Aug. 1, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted an aggregate of 333 restricted stock units (RSUs) to one newly-hired employee.

    https://images.financialmodelingprep.com/news/karyopharm-therapeutics-kpti-expected-to-beat-earnings-estimates-what-20250729.jpg
    Karyopharm Therapeutics (KPTI) Expected to Beat Earnings Estimates: What to Know Ahead of Q2 Release

    zacks.com

    2025-07-29 11:01:09

    Karyopharm Therapeutics (KPTI) possesses the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.

    https://images.financialmodelingprep.com/news/karyopharm-therapeutics-reports-inducement-grants-under-nasdaq-listing-rule-20250701.jpg
    Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

    prnewswire.com

    2025-07-01 16:05:00

    NEWTON, Mass. , July 1, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted an aggregate of 666 restricted stock units (RSUs) to two newly-hired employees.

    https://images.financialmodelingprep.com/news/karyopharm-to-present-at-the-jefferies-global-healthcare-conference-20250603.jpg
    Karyopharm to Present at the Jefferies Global Healthcare Conference

    prnewswire.com

    2025-06-03 08:00:00

    NEWTON, Mass. , June 3, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company's senior management team is scheduled to present at the Jefferies Global Healthcare Conference on Thursday, June 5, 2025 at 3:10 p.m.

    https://images.financialmodelingprep.com/news/karyopharm-therapeutics-reports-inducement-grants-under-nasdaq-listing-rule-20250602.jpg
    Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

    prnewswire.com

    2025-06-02 16:05:00

    NEWTON, Mass. , June 2, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted an aggregate of 566 restricted stock units (RSUs) to two newly-hired employees.

    https://images.financialmodelingprep.com/news/heres-why-karyopharm-therapeutics-kpti-is-a-great-buy-20250526.jpg
    Here's Why Karyopharm Therapeutics (KPTI) Is a Great 'Buy the Bottom' Stock Now

    zacks.com

    2025-05-26 10:55:15

    Karyopharm Therapeutics (KPTI) witnesses a hammer chart pattern, indicating support found by the stock after losing some value lately. This coupled with an upward trend in earnings estimate revisions could mean a trend reversal for the stock in the near term.