Eaton Vance National Municipal Opportunities Trust (EOT)

As previously reported, 15 out of 16 (94%) patients in Phase 2b in the Per Protocol Population experienced Clinical Cure (CC) and all 15 of 15 (100%) remained free of C. difficile infection (CDI) recurrence through one month after EOT In contrast, 2 of 14 (14%) patients treated with the standard of care, oral vancomycin, experienced recurrent infection within one month after EOT When Phase 2b results are combined with Phase 2a results, 25 of 25 (100%) ibezapolstat-treated patients with CDI who had CC at EOT remained recurrence-free through 1 month after EOT; additionally, all 5 Phase 2b ibezapolstat-treated patients observed for up to 3 months following CC experienced no recurrence of infection Adding to this Lancet Microbe publication, two recent Journal of Antimicrobial Agents and Chemotherapeutics publications regarding, respectively, favorable gut microbiome effects which differentiate IBZ from other anti-CDI antibiotics and positive results from an in-silico study predicting the microbiome-restorative potential of IBZ The totality of ibezapolstat data-to-date further advances Acurx's robust data package and are reshaping the therapeutic landscape for future treatment of CDI with ibezapolstat's innovative and potentially transformative new class of antibiotics to treat gram-positive infections while preserving and restoring the protective gut microbiota Acurx is well positioned to begin international Phase 3 clinical trials and has previously been granted FDA QIDP and Fast-Track Designation and has received SME (Small and Medium-sized Enterprise) designation by the EMA STATEN ISLAND, N.Y.

BOSTON--(BUSINESS WIRE)--The following Eaton Vance closed-end funds (the “Funds”) announced distributions today as detailed below. Declaration – 2/3/2025 Ex-Date – 2/13/2025 Record – 2/13/2025 Payable – 2/24/2025 Municipal Bond Funds:   Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 1/31/25 Distribution Rate at Market Price Eaton Vance California Municipal Income Trust CEV $0.0500 - $10.14 5.92% Eaton Vance Municipal Income Trust EVN $0.0513 - $10.31 5.97% Taxabl.

BOSTON--(BUSINESS WIRE)--The following Eaton Vance closed-end funds (the “Funds”) announced distributions today as detailed below. Declaration – 1/2/2025 Ex-Date – 1/13/2025 Record – 1/13/2025 Payable – 1/22/2025 Municipal Bond Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 12/31/24 Distribution Rate at Market Price Eaton Vance California Municipal Income Trust CEV $0.0500 - $10.04 5.98% Eaton Vance Municipal Income Trust EVN $0.0513 - $10.11 6.09% Taxable.

BOSTON--(BUSINESS WIRE)--The following Eaton Vance closed-end funds (the “Funds”) announced distributions today as detailed below. Declaration – 12/2/2024    Ex-Date – 12/12/2024    Record – 12/12/2024    Payable – 12/19/2024 Municipal Bond Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 11/29/24 Distribution Rate at Market Price Eaton Vance California Municipal Income Trust CEV $0.0500 - $10.65 5.63% Eaton Vance Municipal Income Trust EVN $0.0513 - $10.79.

BOSTON--(BUSINESS WIRE)--The following Eaton Vance closed-end funds (the “Funds”) announced distributions today as detailed below. Declaration – 10/1/2024 Ex-Date – 10/11/2024 Record – 10/11/2024 Payable – 10/18/2024   Municipal Bond Funds:           Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 9/30/24 Distribution Rate at Market Price Eaton Vance California Municipal Income Trust CEV $0.0500 - $10.87 5.52% Eaton Vance Municipal Income Trust EVN $0.0513 - $10.9.

BOSTON--(BUSINESS WIRE)--The following Eaton Vance closed-end funds (the “Funds”) announced distributions today as detailed below. Declaration – 3/1/2024 Ex-Date – 3/8/2024 Record – 3/11/2024 Payable – 3/18/2024   Municipal Bond Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 2/29/24 Distribution Rate at Market Price Eaton Vance California Municipal Income Trust CEV $0.0434 - $10.40 5.01% Eaton Vance Municipal Income Trust EVN $0.0461 - $10.15 5.45%   Taxab.

BOSTON--(BUSINESS WIRE)--The following Eaton Vance closed-end funds (the “Funds”) announced distributions today as detailed below. Declaration – 1/2/2024 Ex-Date – 1/11/2024 Record – 1/12/2024 Payable – 1/19/2024   Municipal Bond Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 12/29/23 Distribution Rate at Market Price Eaton Vance California Municipal Income Trust CEV $0.0434 $0.0092 $10.34 5.04% Eaton Vance Municipal Income Trust EVN $0.0461 $0.0086 $9.82.

19 out of 22 CEF sectors are positive on price, and 21 out of 22 sectors are positive on NAV. KYN/KMF merger completes. NXG Cushing Midstream Energy Fund rights offering begins.

BOSTON--(BUSINESS WIRE)--The following Eaton Vance closed-end funds (the “Funds”) announced distributions today as detailed below. Declaration – 12/1/2023 Ex-Date – 12/8/2023 Record – 12/11/2023 Payable – 12/18/2023             Municipal Bond Funds: Fund   Ticker   Distribution   Change From Prior Distribution   Closing Market Price – 11/30/23   Distribution Rate at Market Price Eaton Vance California Municipal Income Trust   CEV   $0.0342   -   $9.93   4.13% Eaton Vance Municipal Income Trust.

BOSTON--(BUSINESS WIRE)--The following Eaton Vance closed-end funds (the “Funds”) announced distributions today as detailed below.

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BOSTON--(BUSINESS WIRE)--The following Eaton Vance closed-end funds (the “Funds”) announced distributions today as detailed below. Declaration – 7/3/2023 Ex-Date – 7/12/2023 Record – 7/13/2023 Payable – 7/20/2023   Municipal Bond Funds:           Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 6/30/23 Distribution Rate at Market Price Eaton Vance California Municipal Income Trust CEV $0.0342 ($0.0029) $9.99 4.11% Eaton Vance Municipal Income Trust EVN $0.0375 ($0.

BOSTON--(BUSINESS WIRE)--The following Eaton Vance closed-end funds (the “Funds”) announced distributions today as detailed below. Declaration – 5/1/2023 Ex-Date – 5/10/2023 Record – 5/11/2023 Payable – 5/18/2023 Municipal Bond Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 4/28/23 Distribution Rate at Market Price Eaton Vance California Municipal Income Trust CEV $0.0371 - $10.11 4.40% Eaton Vance Municipal Income Trust EVN $0.0410 - $10.20 4.82% Taxable Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 4/28/23 Distribution Rate at Market Price Eaton Vance Senior Income Trust EVF $0.0530 - $5.32 11.95% Eaton Vance Limited Duration Income Fund EVV $0.0787 ($0.0002) $9.35 10.10% Declaration – 5/1/2023 Ex-Date – 5/19/2023 Record – 5/22/2023 Payable – 5/31/2023 Municipal Bond Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 4/28/23 Distribution Rate at Market Price Eaton Vance California Municipal Bond Fund EVM $0.0306 - $8.96 4.10% Eaton Vance Municipal Bond Fund EIM $0.0354 - $10.30 4.12% Eaton Vance Municipal Income 2028 Term Trust ETX $0.0617 - $18.52 4.00% Eaton Vance National Municipal Opportunities Trust EOT $0.0625 - $17.42 4.31% Eaton Vance New York Municipal Bond Fund ENX $0.0297 - $9.68 3.68% Taxable Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 4/28/23 Distribution Rate at Market Price Eaton Vance Floating-Rate Income Trust EFT $0.1110 - $11.61 11.47% Eaton Vance Senior Floating-Rate Trust EFR $0.1030 - $11.53 10.72% Eaton Vance Short Duration Diversified Income Fund EVG $0.0757 ($0.0002) $9.90 9.18% Funds Making Distributions Under a Managed Distribution Plan*: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 4/28/23 Distribution Rate at Market Price Eaton Vance Enhanced Equity Income Fund EOI $0.1095 - $15.54 8.46% Eaton Vance Enhanced Equity Income Fund II EOS $0.1152 - $16.33 8.47% Eaton Vance Risk-Managed Diversified Equity Income Fund ETJ $0.0579 - $7.90 8.79% Eaton Vance Tax-Advantaged Dividend Income Fund EVT $0.1488 - $22.79 7.84% Eaton Vance Tax-Advantaged Global Dividend Income Fund ETG $0.1001 - $16.26 7.39% Eaton Vance Tax-Advantaged Global Dividend Opportunities Fund ETO $0.1374 - $22.32 7.39% Eaton Vance Tax-Managed Buy-Write Income Fund ETB $0.0932 - $12.90 8.67% Eaton Vance Tax-Managed Buy-Write Opportunities Fund ETV $0.0949 - $12.35 9.22% Eaton Vance Tax-Managed Diversified Equity Income Fund ETY $0.0805 - $11.66 8.28% Eaton Vance Tax-Managed Global Buy-Write Opportunities Fund ETW $0.0582 - $8.14 8.58% Eaton Vance Tax-Managed Global Diversified Equity Income Fund EXG $0.0553 - $7.81 8.50% * These Funds make distributions in accordance with a managed distribution plan. Under the managed distribution plan, a Fund issues a notice to shareholders and a press release containing information about the amount and sources of the distribution and other related information on payment date of the distribution. A Fund’s distributions in any period may be more or less than the net return earned by the Fund on its investments, and therefore should not be used as a measure of performance or confused with “yield” or “income.” Distributions in excess of Fund returns will cause its net asset value to erode. Investors should not draw any conclusions about a Fund’s investment performance from the amount of its distribution or from the terms of its managed distribution plan. The Fund’s Board may amend or terminate the managed distribution plan at any time without prior notice to Fund shareholders. The Distribution Rate at Market Price is based on the Fund's most recent regular distribution per share (annualized) divided by the Fund’s market price at the end of the period. Fund distributions may be affected by numerous factors, including changes in Fund performance, the cost of financing for Funds that employ leverage, portfolio holdings, realized and projected returns, and other factors. There can be no assurance that an unanticipated change in market conditions or other unforeseen factors will not result in a change in a Fund’s distributions at a future time. A portion of the distributions may be comprised of amounts from sources other than net investment income. If that is the case, you will be notified in writing. Further information will be available prior to the payment date at funds.eatonvance.com. The final determination of tax characteristics of each Fund’s distributions will occur after the end of the year, at which time it will be reported to the shareholders. Eaton Vance applies in-depth fundamental analysis to the active management of equity, income, alternative and multi-asset strategies. Eaton Vance’s investment teams follow time-tested principles of investing that emphasize ongoing risk management, tax management (where applicable) and the pursuit of consistent long-term returns. The firm’s investment capabilities encompass the global capital markets. With a history dating back to 1924, Eaton Vance is headquartered in Boston and also maintains investment offices in New York, London, Tokyo and Singapore. For more information, visit evmanagement.com. Eaton Vance is a part of Morgan Stanley Investment Management, the asset management division of Morgan Stanley. Shares of closed-end funds often trade at a discount from their net asset value. The market price of Fund shares may vary from net asset value based on factors affecting the supply and demand for shares, such as Fund distribution rates relative to similar investments, investors’ expectations for future distribution changes, the clarity of the Fund’s investment strategy and future return expectations, and investors’ confidence in the underlying markets in which the Fund invests. Fund shares are subject to investment risk, including possible loss of principal invested. No Fund is a complete investment program and you may lose money investing in a Fund. An investment in a Fund may not be appropriate for all investors. Before investing, prospective investors should consider carefully the Fund’s investment objective, risks, charges and expenses.

BOSTON--(BUSINESS WIRE)--The following Eaton Vance closed-end funds (the “Funds”) announced distributions today as detailed below. Declaration – 4/3/2023 Ex-Date – 4/12/2023 Record – 4/13/2023 Payable – 4/20/2023 Municipal Bond Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 3/31/23 Distribution Rate at Market Price Eaton Vance California Municipal Income Trust CEV $0.0371 - $10.23 4.35% Eaton Vance Municipal Income Trust EVN $0.0410 - $10.13 4.86% Taxable Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 3/31/23 Distribution Rate at Market Price Eaton Vance Senior Income Trust EVF $0.0530 - $5.35 11.89% Eaton Vance Limited Duration Income Fund EVV $0.0789 ($0.0211) $9.85 9.61% Declaration – 4/3/2023 Ex-Date – 4/21/2023 Record – 4/24/2023 Payable – 4/28/2023 Municipal Bond Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 3/31/23 Distribution Rate at Market Price Eaton Vance California Municipal Bond Fund EVM $0.0306 - $9.02 4.07% Eaton Vance Municipal Bond Fund EIM $0.0354 - $10.40 4.08% Eaton Vance Municipal Income 2028 Term Trust ETX $0.0617 - $17.79 4.16% Eaton Vance National Municipal Opportunities Trust EOT $0.0625 - $17.67 4.24% Eaton Vance New York Municipal Bond Fund ENX $0.0297 - $9.72 3.66% Taxable Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 3/31/23 Distribution Rate at Market Price Eaton Vance Floating-Rate Income Trust EFT $0.1110 $0.0050 $11.51 11.57% Eaton Vance Senior Floating-Rate Trust EFR $0.1030 $0.0010 $11.33 10.91% Eaton Vance Short Duration Diversified Income Fund EVG $0.0759 ($0.0141) $10.45 8.72% Funds Making Distributions Under a Managed Distribution Plan*: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 3/31/23 Distribution Rate at Market Price Eaton Vance Enhanced Equity Income Fund EOI $0.1095 - $15.22 8.63% Eaton Vance Enhanced Equity Income Fund II EOS $0.1152 - $16.40 8.43% Eaton Vance Risk-Managed Diversified Equity Income Fund ETJ $0.0579 - $7.95 8.74% Eaton Vance Tax-Advantaged Dividend Income Fund EVT $0.1488 - $22.61 7.90% Eaton Vance Tax-Advantaged Global Dividend Income Fund ETG $0.1001 - $16.15 7.44% Eaton Vance Tax-Advantaged Global Dividend Opportunities Fund ETO $0.1374 - $22.23 7.42% Eaton Vance Tax-Managed Buy-Write Income Fund ETB $0.0932 - $13.05 8.57% Eaton Vance Tax-Managed Buy-Write Opportunities Fund ETV $0.0949 - $12.63 9.02% Eaton Vance Tax-Managed Diversified Equity Income Fund ETY $0.0805 - $11.67 8.28% Eaton Vance Tax-Managed Global Buy-Write Opportunities Fund ETW $0.0582 - $8.08 8.64% Eaton Vance Tax-Managed Global Diversified Equity Income Fund EXG $0.0553 - $7.81 8.50% * These Funds make distributions in accordance with a managed distribution plan. Under the managed distribution plan, a Fund issues a notice to shareholders and a press release containing information about the amount and sources of the distribution and other related information on payment date of the distribution. A Fund’s distributions in any period may be more or less than the net return earned by the Fund on its investments, and therefore should not be used as a measure of performance or confused with “yield” or “income.” Distributions in excess of Fund returns will cause its net asset value to erode. Investors should not draw any conclusions about a Fund’s investment performance from the amount of its distribution or from the terms of its managed distribution plan. The Fund’s Board may amend or terminate the managed distribution plan at any time without prior notice to Fund shareholders. The Distribution Rate at Market Price is based on the Fund's most recent regular distribution per share (annualized) divided by the Fund’s market price at the end of the period. Fund distributions may be affected by numerous factors, including changes in Fund performance, the cost of financing for Funds that employ leverage, portfolio holdings, realized and projected returns, and other factors. There can be no assurance that an unanticipated change in market conditions or other unforeseen factors will not result in a change in a Fund’s distributions at a future time. A portion of the distributions may be comprised of amounts from sources other than net investment income. If that is the case, you will be notified in writing. Further information will be available prior to the payment date at funds.eatonvance.com. The final determination of tax characteristics of each Fund’s distributions will occur after the end of the year, at which time it will be reported to the shareholders. Eaton Vance applies in-depth fundamental analysis to the active management of equity, income, alternative and multi-asset strategies. Eaton Vance’s investment teams follow time-tested principles of investing that emphasize ongoing risk management, tax management (where applicable) and the pursuit of consistent long-term returns. The firm’s investment capabilities encompass the global capital markets. With a history dating back to 1924, Eaton Vance is headquartered in Boston and also maintains investment offices in New York, London, Tokyo and Singapore. For more information, visit evmanagement.com. Eaton Vance is a part of Morgan Stanley Investment Management, the asset management division of Morgan Stanley. Shares of closed-end funds often trade at a discount from their net asset value. The market price of Fund shares may vary from net asset value based on factors affecting the supply and demand for shares, such as Fund distribution rates relative to similar investments, investors’ expectations for future distribution changes, the clarity of the Fund’s investment strategy and future return expectations, and investors’ confidence in the underlying markets in which the Fund invests. Fund shares are subject to investment risk, including possible loss of principal invested. No Fund is a complete investment program and you may lose money investing in a Fund. An investment in a Fund may not be appropriate for all investors. Before investing, prospective investors should consider carefully the Fund’s investment objective, risks, charges and expenses.

Three out of 22 CEF sectors positive on price and 5 out of 22 sectors positive on NAV last week. Delaware/Abrdn mergers are closed.

BOSTON--(BUSINESS WIRE)--The following Eaton Vance closed-end funds (the “Funds”) announced distributions today as detailed below. Municipal Bond Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 2/28/23 Distribution Rate at Market Price Eaton Vance California Municipal Income Trust CEV $0.0371 - $9.96 4.47% Eaton Vance Municipal Income Trust EVN $0.0410 - $10.02 4.91% Taxable Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 2/28/23 Rate at Market Price Eaton Vance Senior Income Trust EVF $0.0530 $0.0010 $5.70 Eaton Vance Limited Duration Income Fund EVV $0.1000 - $10.19 Municipal Bond Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 2/28/23 Distribution Rate at Market Price Eaton Vance California Municipal Bond Fund EVM $0.0306 - $8.81 4.17% Eaton Vance Municipal Bond Fund EIM $0.0354 - $9.97 4.26% Eaton Vance Municipal Income 2028 Term Trust ETX $0.0617 - $17.76 4.17% Eaton Vance National Municipal Opportunities Trust EOT $0.0625 - $17.78 4.22% Eaton Vance New York Municipal Bond Fund ENX $0.0297 - $9.18 3.88% Taxable Funds: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 2/28/23 Distribution Rate at Market Price Eaton Vance Floating-Rate Income Trust EFT $0.1060 $0.0020 $12.02 10.58% Eaton Vance Senior Floating-Rate Trust EFR $0.1020 $0.0030 $11.94 10.25% Eaton Vance Short Duration Diversified Income Fund EVG $0.0900 ($0.0013) $10.62 10.17% Funds Making Distributions Under a Managed Distribution Plan*: Fund Ticker Distribution Change From Prior Distribution Closing Market Price – 2/28/23 Distribution Rate at Market Price Eaton Vance Enhanced Equity Income Fund EOI $0.1095 - $15.66 8.39% Eaton Vance Enhanced Equity Income Fund II EOS $0.1152 - $16.24 8.51% Eaton Vance Risk-Managed Diversified Equity Income Fund ETJ $0.0579 - $7.79 8.92% Eaton Vance Tax-Advantaged Dividend Income Fund EVT $0.1488 - $23.26 7.68% Eaton Vance Tax-Advantaged Global Dividend Income Fund ETG $0.1001 - $15.88 7.56% Eaton Vance Tax-Advantaged Global Dividend Opportunities Fund ETO $0.1374 - $21.85 7.55% Eaton Vance Tax-Managed Buy-Write Income Fund ETB $0.0932 - $13.23 8.45% Eaton Vance Tax-Managed Buy-Write Opportunities Fund ETV $0.0949 - $12.98 8.77% Eaton Vance Tax-Managed Buy-Write Strategy Fund EXD $0.0708 - $9.88 8.60% Eaton Vance Tax-Managed Diversified Equity Income Fund ETY $0.0805 - $11.71 8.25% Eaton Vance Tax-Managed Global Buy-Write Opportunities Fund ETW $0.0582 - $7.98 8.75% Eaton Vance Tax-Managed Global Diversified Equity Income Fund EXG $0.0553 - $7.62 8.71% * These Funds make distributions in accordance with a managed distribution plan. Under the managed distribution plan, a Fund issues a notice to shareholders and a press release containing information about the amount and sources of the distribution and other related information on payment date of the distribution. A Fund’s distributions in any period may be more or less than the net return earned by the Fund on its investments, and therefore should not be used as a measure of performance or confused with “yield” or “income.” Distributions in excess of Fund returns will cause its net asset value to erode. Investors should not draw any conclusions about a Fund’s investment performance from the amount of its distribution or from the terms of its managed distribution plan. The Fund’s Board may amend or terminate the managed distribution plan at any time without prior notice to Fund shareholders. The Distribution Rate at Market Price is based on the Fund's most recent regular distribution per share (annualized) divided by the Fund’s market price at the end of the period. Fund distributions may be affected by numerous factors, including changes in Fund performance, the cost of financing for Funds that employ leverage, portfolio holdings, realized and projected returns, and other factors. There can be no assurance that an unanticipated change in market conditions or other unforeseen factors will not result in a change in a Fund’s distributions at a future time. A portion of the distributions may be comprised of amounts from sources other than net investment income. If that is the case, you will be notified in writing. Further information will be available prior to the payment date at funds.eatonvance.com. The final determination of tax characteristics of each Fund’s distributions will occur after the end of the year, at which time it will be reported to the shareholders. Eaton Vance applies in-depth fundamental analysis to the active management of equity, income, alternative and multi-asset strategies. Eaton Vance’s investment teams follow time-tested principles of investing that emphasize ongoing risk management, tax management (where applicable) and the pursuit of consistent long-term returns. The firm’s investment capabilities encompass the global capital markets. With a history dating back to 1924, Eaton Vance is headquartered in Boston and also maintains investment offices in New York, London, Tokyo and Singapore. For more information, visit evmanagement.com. Eaton Vance is a part of Morgan Stanley Investment Management, the asset management division of Morgan Stanley. Shares of closed-end funds often trade at a discount from their net asset value. The market price of Fund shares may vary from net asset value based on factors affecting the supply and demand for shares, such as Fund distribution rates relative to similar investments, investors’ expectations for future distribution changes, the clarity of the Fund’s investment strategy and future return expectations, and investors’ confidence in the underlying markets in which the Fund invests. Fund shares are subject to investment risk, including possible loss of principal invested. No Fund is a complete investment program and you may lose money investing in a Fund. An investment in a Fund may not be appropriate for all investors. Before investing, prospective investors should consider carefully the Fund’s investment objective, risks, charges and expenses.