Castle Biosciences, Inc. (CSTL)
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Castle Biosciences, Inc., a commercial-stage diagnostics company, focuses to provide diagnostic and prognostic testing services for dermatological cancers. Its lead product is DecisionDx-Melanoma, a multi-gene expression profile (GEP) test to identify the risk of metastasis for patients diagnosed with invasive cutaneous melanoma. The company also offers DecisionDx-UM test, a proprietary GEP test that predicts the risk of metastasis for patients with uveal melanoma, a rare eye cancer; DecisionDx-SCC, a proprietary 40-gene expression profile test that uses an individual patient's tumor biology to predict individual risk of squamous cell carcinoma metastasis for patients with one or more risk factors; and DecisionDx DiffDx-Melanoma and myPath Melanoma, a proprietary GEP test to diagnose suspicious pigmented lesions. It offers test services through physicians and their patients. The company was founded in 2007 and is headquartered in Friendswood, Texas.
NEWS

Castle Biosciences' Founder, President and CEO Derek Maetzold Honored with the CEO of the Year Award by The CEO Magazine
globenewswire.com
2025-10-01 16:30:00FRIENDSWOOD, Texas, Oct. 01, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that its founder, president and chief executive officer Derek Maetzold has been awarded the CEO of the Year by The CEO Magazine. The Executive of the Year Awards program recognizes senior executives driving measurable impact, innovation and inspiration.

Castle Biosciences Honored with a Greater Pittsburgh Top Workplaces 2025 Award
globenewswire.com
2025-09-23 07:00:00FRIENDSWOOD, Texas, Sept. 23, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that it has been recognized as a Greater Pittsburgh Top Workplace by The Pittsburgh Post-Gazette.

Castle Biosciences Named One of Newsweek's America's Greatest Companies 2025
globenewswire.com
2025-09-17 07:00:00FRIENDSWOOD, Texas, Sept. 17, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, has been included in the inaugural 2025 America's Greatest Companies list, published by Newsweek.

New Data at American Foregut Society's 2025 Annual Meeting Demonstrates TissueCypher® Can Detect High-Risk Barrett's Esophagus Patients Not Identified by Pathology to Support Improved Care Decisions
globenewswire.com
2025-09-09 07:00:00FRIENDSWOOD, Texas, Sept. 09, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that new data demonstrating the personalized risk stratification provided by its TissueCypher Barrett's Esophagus test will be shared via a podium presentation at the American Foregut Society's (AFS) 2025 Annual Meeting, taking place Sept.

Castle Biosciences: Strong Margins, Solid Balance Sheet, And Big Upside Potential
seekingalpha.com
2025-09-02 09:14:49Castle Biosciences effectively translates complex diagnostics into a scalable, high-margin business, with strong clinical demand and a robust balance sheet supporting long-term growth. The investment thesis centers on margin expansion and payer coverage; current valuation does not reflect the company's profit potential or future margin upside. Key risks include reimbursement uncertainty for DecisionDx-SCC and insurer behavior, but Castle's cash reserves and diversified test portfolio provide a cushion.

New Evidence Published Supporting Use of DecisionDx®-SCC Test in Guiding and Improving Treatment Pathway Decisions in NCCN High-Risk Cutaneous Squamous Cell Carcinoma
globenewswire.com
2025-08-25 07:00:00New validation study shows DecisionDx-SCC significantly outperforms current staging systems in predicting risk of local recurrence and metastasis for NCCN high-risk patients Clinician survey confirms test results align with treatment decision-making thresholds for adjuvant radiation therapy and surveillance imaging FRIENDSWOOD, Texas, Aug. 25, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced the publication of two new studies related to its DecisionDx-SCC test, adding to its validated uses for patients with high-risk cutaneous squamous cell carcinoma (SCC).1,2 DecisionDx-SCC is a gene expression profile test (40-GEP) designed to use a patient's tumor biology to predict individual risk of metastasis as well as response to adjuvant radiation therapy (ART). The first study represents an expanded clinical use milestone, demonstrating that DecisionDx-SCC predicts local recurrence in patients classified as high-risk by National Comprehensive Cancer Network (NCCN) guidelines who have undergone Mohs resection, thereby adding a third use to the test's existing capabilities.

Castle Biosciences to Participate in Upcoming Investor Conferences
globenewswire.com
2025-08-21 07:00:00FRIENDSWOOD, Texas, Aug. 21, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that its executive management is scheduled to present a company overview at Baird's 2025 Global Healthcare Conference on Wednesday, Sept. 10, 2025, at 10:15 a.m.

Castle Biosciences, Inc. (CSTL) Q2 2025 Earnings Call Transcript
seekingalpha.com
2025-08-04 22:21:49Castle Biosciences, Inc. (NASDAQ:CSTL ) Q2 2025 Earnings Conference Call August 4, 2025 4:30 PM ET Company Participants Camilla Zuckero - Vice President of Investor Relations & Corporate Affairs Derek J. Maetzold - Founder, CEO, President & Director Frank Stokes - CFO & Treasurer Conference Call Participants Catherine Walden Ramsey Schulte - Robert W.

Castle (CSTL) Q2 Revenue Tops Estimates
fool.com
2025-08-04 20:50:24Castle (CSTL) Q2 Revenue Tops Estimates

Castle Biosciences, Inc. (CSTL) Q2 Earnings and Revenues Surpass Estimates
zacks.com
2025-08-04 18:21:14Castle Biosciences, Inc. (CSTL) came out with quarterly earnings of $0.15 per share, beating the Zacks Consensus Estimate of a loss of $0.51 per share. This compares to earnings of $0.31 per share a year ago.

Castle Biosciences Reports Second Quarter 2025 Results
globenewswire.com
2025-08-04 16:05:00Delivered Q2 2025 revenue of $86 million Q 2 2025 total test reports for our core revenue drivers (DecisionDx ® -Melanoma, TissueCypher ® ) increased 33% over Q 2 2024 Raising full-year 2025 revenue guidance range to $310-320 million from $287-297 million Conference call and webcast today at 4:30 p.m. ET FRIENDSWOOD, Texas, Aug. 04, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced its financial results for the second quarter and six months ended June 30, 2025.

New Strong Sell Stocks for August 1st
zacks.com
2025-08-01 06:16:04CRSP, CSTL and SIGI have been added to the Zacks Rank #5 (Strong Sell) List on August 1, 2025.

Castle Biosciences to Present at the Canaccord Genuity 45th Annual Growth Conference
globenewswire.com
2025-07-29 07:00:00Castle Biosciences' executive management will present a company overview at the Canaccord Genuity 45th Annual Growth Conference Aug. 12, 2025 at 12:30pm ET

Earnings Preview: Castle Biosciences, Inc. (CSTL) Q2 Earnings Expected to Decline
zacks.com
2025-07-28 11:06:45Castle Biosciences (CSTL) doesn't possess the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.

Castle Biosciences' Founder, President and CEO Derek Maetzold Named a Most Admired CEO by the Houston Business Journal
globenewswire.com
2025-07-25 07:00:00FRIENDSWOOD, Texas, July 25, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that its founder, president and chief executive officer Derek Maetzold has been named a 2025 Most Admired CEO by the Houston Business Journal. This prestigious honor celebrates leaders who have demonstrated outstanding financial stewardship, fostered inclusive and thriving workplace cultures, and made meaningful contributions to the greater Houston community.

FDA Grants Breakthrough Device Designation to Castle Biosciences' DecisionDx®-Melanoma Test
globenewswire.com
2025-07-23 07:00:00Castle announced that its DecisionDx®-Melanoma test has been granted Breakthrough Device designation from the U.S. Food and Drug Administration (FDA).
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Castle Biosciences' Founder, President and CEO Derek Maetzold Honored with the CEO of the Year Award by The CEO Magazine
globenewswire.com
2025-10-01 16:30:00FRIENDSWOOD, Texas, Oct. 01, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that its founder, president and chief executive officer Derek Maetzold has been awarded the CEO of the Year by The CEO Magazine. The Executive of the Year Awards program recognizes senior executives driving measurable impact, innovation and inspiration.

Castle Biosciences Honored with a Greater Pittsburgh Top Workplaces 2025 Award
globenewswire.com
2025-09-23 07:00:00FRIENDSWOOD, Texas, Sept. 23, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that it has been recognized as a Greater Pittsburgh Top Workplace by The Pittsburgh Post-Gazette.

Castle Biosciences Named One of Newsweek's America's Greatest Companies 2025
globenewswire.com
2025-09-17 07:00:00FRIENDSWOOD, Texas, Sept. 17, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, has been included in the inaugural 2025 America's Greatest Companies list, published by Newsweek.

New Data at American Foregut Society's 2025 Annual Meeting Demonstrates TissueCypher® Can Detect High-Risk Barrett's Esophagus Patients Not Identified by Pathology to Support Improved Care Decisions
globenewswire.com
2025-09-09 07:00:00FRIENDSWOOD, Texas, Sept. 09, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that new data demonstrating the personalized risk stratification provided by its TissueCypher Barrett's Esophagus test will be shared via a podium presentation at the American Foregut Society's (AFS) 2025 Annual Meeting, taking place Sept.

Castle Biosciences: Strong Margins, Solid Balance Sheet, And Big Upside Potential
seekingalpha.com
2025-09-02 09:14:49Castle Biosciences effectively translates complex diagnostics into a scalable, high-margin business, with strong clinical demand and a robust balance sheet supporting long-term growth. The investment thesis centers on margin expansion and payer coverage; current valuation does not reflect the company's profit potential or future margin upside. Key risks include reimbursement uncertainty for DecisionDx-SCC and insurer behavior, but Castle's cash reserves and diversified test portfolio provide a cushion.

New Evidence Published Supporting Use of DecisionDx®-SCC Test in Guiding and Improving Treatment Pathway Decisions in NCCN High-Risk Cutaneous Squamous Cell Carcinoma
globenewswire.com
2025-08-25 07:00:00New validation study shows DecisionDx-SCC significantly outperforms current staging systems in predicting risk of local recurrence and metastasis for NCCN high-risk patients Clinician survey confirms test results align with treatment decision-making thresholds for adjuvant radiation therapy and surveillance imaging FRIENDSWOOD, Texas, Aug. 25, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced the publication of two new studies related to its DecisionDx-SCC test, adding to its validated uses for patients with high-risk cutaneous squamous cell carcinoma (SCC).1,2 DecisionDx-SCC is a gene expression profile test (40-GEP) designed to use a patient's tumor biology to predict individual risk of metastasis as well as response to adjuvant radiation therapy (ART). The first study represents an expanded clinical use milestone, demonstrating that DecisionDx-SCC predicts local recurrence in patients classified as high-risk by National Comprehensive Cancer Network (NCCN) guidelines who have undergone Mohs resection, thereby adding a third use to the test's existing capabilities.

Castle Biosciences to Participate in Upcoming Investor Conferences
globenewswire.com
2025-08-21 07:00:00FRIENDSWOOD, Texas, Aug. 21, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that its executive management is scheduled to present a company overview at Baird's 2025 Global Healthcare Conference on Wednesday, Sept. 10, 2025, at 10:15 a.m.

Castle Biosciences, Inc. (CSTL) Q2 2025 Earnings Call Transcript
seekingalpha.com
2025-08-04 22:21:49Castle Biosciences, Inc. (NASDAQ:CSTL ) Q2 2025 Earnings Conference Call August 4, 2025 4:30 PM ET Company Participants Camilla Zuckero - Vice President of Investor Relations & Corporate Affairs Derek J. Maetzold - Founder, CEO, President & Director Frank Stokes - CFO & Treasurer Conference Call Participants Catherine Walden Ramsey Schulte - Robert W.

Castle (CSTL) Q2 Revenue Tops Estimates
fool.com
2025-08-04 20:50:24Castle (CSTL) Q2 Revenue Tops Estimates

Castle Biosciences, Inc. (CSTL) Q2 Earnings and Revenues Surpass Estimates
zacks.com
2025-08-04 18:21:14Castle Biosciences, Inc. (CSTL) came out with quarterly earnings of $0.15 per share, beating the Zacks Consensus Estimate of a loss of $0.51 per share. This compares to earnings of $0.31 per share a year ago.

Castle Biosciences Reports Second Quarter 2025 Results
globenewswire.com
2025-08-04 16:05:00Delivered Q2 2025 revenue of $86 million Q 2 2025 total test reports for our core revenue drivers (DecisionDx ® -Melanoma, TissueCypher ® ) increased 33% over Q 2 2024 Raising full-year 2025 revenue guidance range to $310-320 million from $287-297 million Conference call and webcast today at 4:30 p.m. ET FRIENDSWOOD, Texas, Aug. 04, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced its financial results for the second quarter and six months ended June 30, 2025.

New Strong Sell Stocks for August 1st
zacks.com
2025-08-01 06:16:04CRSP, CSTL and SIGI have been added to the Zacks Rank #5 (Strong Sell) List on August 1, 2025.

Castle Biosciences to Present at the Canaccord Genuity 45th Annual Growth Conference
globenewswire.com
2025-07-29 07:00:00Castle Biosciences' executive management will present a company overview at the Canaccord Genuity 45th Annual Growth Conference Aug. 12, 2025 at 12:30pm ET

Earnings Preview: Castle Biosciences, Inc. (CSTL) Q2 Earnings Expected to Decline
zacks.com
2025-07-28 11:06:45Castle Biosciences (CSTL) doesn't possess the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.

Castle Biosciences' Founder, President and CEO Derek Maetzold Named a Most Admired CEO by the Houston Business Journal
globenewswire.com
2025-07-25 07:00:00FRIENDSWOOD, Texas, July 25, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that its founder, president and chief executive officer Derek Maetzold has been named a 2025 Most Admired CEO by the Houston Business Journal. This prestigious honor celebrates leaders who have demonstrated outstanding financial stewardship, fostered inclusive and thriving workplace cultures, and made meaningful contributions to the greater Houston community.

FDA Grants Breakthrough Device Designation to Castle Biosciences' DecisionDx®-Melanoma Test
globenewswire.com
2025-07-23 07:00:00Castle announced that its DecisionDx®-Melanoma test has been granted Breakthrough Device designation from the U.S. Food and Drug Administration (FDA).