Alnylam Pharmaceuticals, Inc. (ALNY)
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Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing, and commercializing novel therapeutics based on ribonucleic acid interference. The company's pipeline of investigational RNAi therapeutics focuses on genetic medicines, cardio-metabolic diseases, hepatic infectious diseases, and central nervous system (CNS)/ocular diseases. Its marketed products include ONPATTRO (patisiran), a lipid complex injection for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; GIVLAARI for the treatment of adults with acute hepatic porphyria (AHP); and OXLUMO (lumasiran) for the treatment of primary hyperoxaluria type 1 (PH1). In addition, the company is developing givosiran for the treatment of adolescent patients with AHP; patisiran for the treatment of transthyretin amyloidosis, or ATTR amyloidosis, with cardiomyopathy; cemdisiran to treat complement-mediated diseases; ALN-AAT02 for the treatment of AAT deficiency-associated liver disease; ALN-HBV02 to treat chronic HBV infection; Zilebesiran to treat hypertension; and ALN-HSD to treat NASH. Further, it offers Fitusiran for the treatment of hemophilia and rare bleeding disorders, Inclisiran to treat hypercholesterolemia, lumasiran for the treatment of advanced PH1 and recurrent renal stones, and vutrisiran for the treatment of ATTR amyloidosis, which is in phase 3 clinical trial. Alnylam Pharmaceuticals, Inc. has strategic collaborations with Regeneron Pharmaceuticals, Inc. to discover, develop, and commercialize RNAi therapeutics for a range of diseases by addressing therapeutic targets expressed in the eye and CNS; and Sanofi Genzyme to discover, develop, and commercialize RNAi therapeutics. It also has license and collaboration agreements with Novartis AG; Vir Biotechnology, Inc.; Dicerna Pharmaceuticals, Inc.; Ionis Pharmaceuticals, Inc.; and PeptiDream, Inc. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts.
NEWS

GSK Strikes $1 Billion China RNA Deal
gurufocus.com
2026-02-24 11:43:00GSK plc (GSK) is making a calculated bet on next generation gene silencing drugs, signing a licensing agreement worth up to $1 billion with China's Frontier Bio

Alnylam to Webcast Presentation at TD Cowen 46th Annual Health Care Conference
businesswire.com
2026-02-23 10:00:00CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that management will present a company overview at the TD Cowen 46th Annual Healthcare Conference on Monday, March 2, 2026 at 9:10 am ET. A live audio webcast of the presentation will be available on the Investors section of the Company's website, www.alnylam.com/events. A replay will be available on the Alnylam website within 48 hours after the event. About Al.

Alnylam Pharmaceuticals, Inc. $ALNY Shares Bought by Lansforsakringar Fondforvaltning AB publ
defenseworld.net
2026-02-23 06:05:52Lansforsakringar Fondforvaltning AB publ raised its stake in shares of Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 5.4% in the third quarter, according to the company in its most recent disclosure with the Securities and Exchange Commission (SEC). The fund owned 42,404 shares of the biopharmaceutical company's stock after acquiring an additional 2,173 shares

Drug-Delivery Breakthroughs, Cross-Indication Research Accelerate New Momentum in CNS and Oncology Development
globenewswire.com
2026-02-19 08:30:00AUSTIN, Texas, Feb. 19, 2026 (GLOBE NEWSWIRE) -- BioMedWire Editorial Coverage: Biotechnology mergers and acquisitions (M&As) are increasingly shaped by a clear strategic evolution. Pharmaceutical companies are prioritizing clinical-stage and late-stage programs supported by human data rather than early discovery platforms with uncertain timelines.

Alnylam Pharmaceuticals, Inc. $ALNY Shares Purchased by Merit Financial Group LLC
defenseworld.net
2026-02-18 04:48:49Merit Financial Group LLC increased its holdings in shares of Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 123.9% during the undefined quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission. The firm owned 4,232 shares of the biopharmaceutical company's stock after buying an additional 2,342 shares during the

Alnylam Pharmaceuticals, Inc. $ALNY Shares Sold by Skandinaviska Enskilda Banken AB publ
defenseworld.net
2026-02-18 04:15:06Skandinaviska Enskilda Banken AB publ decreased its position in Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 6.2% in the third quarter, according to its most recent 13F filing with the Securities and Exchange Commission (SEC). The fund owned 79,652 shares of the biopharmaceutical company's stock after selling 5,236 shares during the period. Skandinaviska Enskilda

Why Alnylam Pharmaceuticals Stock Was Soaring on Monday
fool.com
2026-02-17 15:27:57Two analysts weighed in with new evaluations of the biotech. This followed last week's earnings release.

Principal Financial Group Inc. Sells 45,114 Shares of Alnylam Pharmaceuticals, Inc. $ALNY
defenseworld.net
2026-02-17 04:50:50Principal Financial Group Inc. cut its position in shares of Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 89.3% during the undefined quarter, according to its most recent filing with the Securities and Exchange Commission (SEC). The fund owned 5,420 shares of the biopharmaceutical company's stock after selling 45,114 shares during the period. Principal Financial

Aberdeen Group plc Sells 61,228 Shares of Alnylam Pharmaceuticals, Inc. $ALNY
defenseworld.net
2026-02-16 03:16:55Aberdeen Group plc lessened its stake in Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 28.0% in the undefined quarter, according to its most recent disclosure with the Securities and Exchange Commission. The firm owned 157,396 shares of the biopharmaceutical company's stock after selling 61,228 shares during the quarter. Aberdeen Group plc owned 0.12% of

Alnylam Hit Hard As Investors Forced To Revise Future Profit Expectations
seekingalpha.com
2026-02-13 15:07:01Alnylam Pharmaceuticals has declined nearly 40% from its all-time high, pressured by near-term TTR market dynamics and longer-term profitability concerns. The TTR business will likely remain "noisy" in the first half of 2026, but Amvuttra continues to gain share, and management guidance for 2026 was above expectations. Management alarmed the Street earlier this year with long-term spending guidance that was considerably higher than expected; management continues to prioritize R&D to realize the company's full long-term potential.

ALNY Q4 Earnings Beat, Sales Miss Despite Y/Y Growth, Stock Down
zacks.com
2026-02-13 11:20:19Alnylam tops Q4 earnings estimates but misses on sales despite 85% revenue growth, as booming Amvuttra demand fails to lift shares.

Why Alnylam Pharmaceuticals Stock Slipped Today
fool.com
2026-02-12 19:42:32The biotech released its final set of figures for 2025. It had a mixed quarter, despite the recent success of a popular product.

Alnylam Pharmaceuticals, Inc. (ALNY) Q4 2025 Earnings Call Transcript
seekingalpha.com
2026-02-12 16:14:23Alnylam Pharmaceuticals, Inc. (ALNY) Q4 2025 Earnings Call Transcript

Here's What Key Metrics Tell Us About Alnylam (ALNY) Q4 Earnings
zacks.com
2026-02-12 11:01:18Although the revenue and EPS for Alnylam (ALNY) give a sense of how its business performed in the quarter ended December 2025, it might be worth considering how some key metrics compare with Wall Street estimates and the year-ago numbers.

Alnylam Pharmaceuticals (ALNY) Surpasses Q4 Earnings Estimates
zacks.com
2026-02-12 10:11:11Alnylam Pharmaceuticals (ALNY) came out with quarterly earnings of $1.25 per share, beating the Zacks Consensus Estimate of $1.16 per share. This compares to earnings of $0.06 per share a year ago.

Alnylam Pharmaceuticals Reports Fourth Quarter and Full Year 2025 Financial Results and Highlights Recent Period Progress
businesswire.com
2026-02-12 08:00:00CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today reported its consolidated financial results for the fourth quarter and full year ended December 31, 2025 and reviewed recent business highlights. “2025 was a year of key accomplishments for Alnylam, highlighted by the landmark approval of AMVUTTRA for ATTR-CM in the U.S., which drove total net product revenues of nearly $3 billion, or 81% growth year-over-year, and prope.
No data to display

GSK Strikes $1 Billion China RNA Deal
gurufocus.com
2026-02-24 11:43:00GSK plc (GSK) is making a calculated bet on next generation gene silencing drugs, signing a licensing agreement worth up to $1 billion with China's Frontier Bio

Alnylam to Webcast Presentation at TD Cowen 46th Annual Health Care Conference
businesswire.com
2026-02-23 10:00:00CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that management will present a company overview at the TD Cowen 46th Annual Healthcare Conference on Monday, March 2, 2026 at 9:10 am ET. A live audio webcast of the presentation will be available on the Investors section of the Company's website, www.alnylam.com/events. A replay will be available on the Alnylam website within 48 hours after the event. About Al.

Alnylam Pharmaceuticals, Inc. $ALNY Shares Bought by Lansforsakringar Fondforvaltning AB publ
defenseworld.net
2026-02-23 06:05:52Lansforsakringar Fondforvaltning AB publ raised its stake in shares of Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 5.4% in the third quarter, according to the company in its most recent disclosure with the Securities and Exchange Commission (SEC). The fund owned 42,404 shares of the biopharmaceutical company's stock after acquiring an additional 2,173 shares

Drug-Delivery Breakthroughs, Cross-Indication Research Accelerate New Momentum in CNS and Oncology Development
globenewswire.com
2026-02-19 08:30:00AUSTIN, Texas, Feb. 19, 2026 (GLOBE NEWSWIRE) -- BioMedWire Editorial Coverage: Biotechnology mergers and acquisitions (M&As) are increasingly shaped by a clear strategic evolution. Pharmaceutical companies are prioritizing clinical-stage and late-stage programs supported by human data rather than early discovery platforms with uncertain timelines.

Alnylam Pharmaceuticals, Inc. $ALNY Shares Purchased by Merit Financial Group LLC
defenseworld.net
2026-02-18 04:48:49Merit Financial Group LLC increased its holdings in shares of Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 123.9% during the undefined quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission. The firm owned 4,232 shares of the biopharmaceutical company's stock after buying an additional 2,342 shares during the

Alnylam Pharmaceuticals, Inc. $ALNY Shares Sold by Skandinaviska Enskilda Banken AB publ
defenseworld.net
2026-02-18 04:15:06Skandinaviska Enskilda Banken AB publ decreased its position in Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 6.2% in the third quarter, according to its most recent 13F filing with the Securities and Exchange Commission (SEC). The fund owned 79,652 shares of the biopharmaceutical company's stock after selling 5,236 shares during the period. Skandinaviska Enskilda

Why Alnylam Pharmaceuticals Stock Was Soaring on Monday
fool.com
2026-02-17 15:27:57Two analysts weighed in with new evaluations of the biotech. This followed last week's earnings release.

Principal Financial Group Inc. Sells 45,114 Shares of Alnylam Pharmaceuticals, Inc. $ALNY
defenseworld.net
2026-02-17 04:50:50Principal Financial Group Inc. cut its position in shares of Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 89.3% during the undefined quarter, according to its most recent filing with the Securities and Exchange Commission (SEC). The fund owned 5,420 shares of the biopharmaceutical company's stock after selling 45,114 shares during the period. Principal Financial

Aberdeen Group plc Sells 61,228 Shares of Alnylam Pharmaceuticals, Inc. $ALNY
defenseworld.net
2026-02-16 03:16:55Aberdeen Group plc lessened its stake in Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 28.0% in the undefined quarter, according to its most recent disclosure with the Securities and Exchange Commission. The firm owned 157,396 shares of the biopharmaceutical company's stock after selling 61,228 shares during the quarter. Aberdeen Group plc owned 0.12% of

Alnylam Hit Hard As Investors Forced To Revise Future Profit Expectations
seekingalpha.com
2026-02-13 15:07:01Alnylam Pharmaceuticals has declined nearly 40% from its all-time high, pressured by near-term TTR market dynamics and longer-term profitability concerns. The TTR business will likely remain "noisy" in the first half of 2026, but Amvuttra continues to gain share, and management guidance for 2026 was above expectations. Management alarmed the Street earlier this year with long-term spending guidance that was considerably higher than expected; management continues to prioritize R&D to realize the company's full long-term potential.

ALNY Q4 Earnings Beat, Sales Miss Despite Y/Y Growth, Stock Down
zacks.com
2026-02-13 11:20:19Alnylam tops Q4 earnings estimates but misses on sales despite 85% revenue growth, as booming Amvuttra demand fails to lift shares.

Why Alnylam Pharmaceuticals Stock Slipped Today
fool.com
2026-02-12 19:42:32The biotech released its final set of figures for 2025. It had a mixed quarter, despite the recent success of a popular product.

Alnylam Pharmaceuticals, Inc. (ALNY) Q4 2025 Earnings Call Transcript
seekingalpha.com
2026-02-12 16:14:23Alnylam Pharmaceuticals, Inc. (ALNY) Q4 2025 Earnings Call Transcript

Here's What Key Metrics Tell Us About Alnylam (ALNY) Q4 Earnings
zacks.com
2026-02-12 11:01:18Although the revenue and EPS for Alnylam (ALNY) give a sense of how its business performed in the quarter ended December 2025, it might be worth considering how some key metrics compare with Wall Street estimates and the year-ago numbers.

Alnylam Pharmaceuticals (ALNY) Surpasses Q4 Earnings Estimates
zacks.com
2026-02-12 10:11:11Alnylam Pharmaceuticals (ALNY) came out with quarterly earnings of $1.25 per share, beating the Zacks Consensus Estimate of $1.16 per share. This compares to earnings of $0.06 per share a year ago.

Alnylam Pharmaceuticals Reports Fourth Quarter and Full Year 2025 Financial Results and Highlights Recent Period Progress
businesswire.com
2026-02-12 08:00:00CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today reported its consolidated financial results for the fourth quarter and full year ended December 31, 2025 and reviewed recent business highlights. “2025 was a year of key accomplishments for Alnylam, highlighted by the landmark approval of AMVUTTRA for ATTR-CM in the U.S., which drove total net product revenues of nearly $3 billion, or 81% growth year-over-year, and prope.










